This here is a trilogy by director Guillermo del Tori and co-author Chuck Hogan (whose work I'm not really familiar with). Perhaps because of this, the book is very visual and cinematic. You can really imagine it happening up on the screen and the pacing feels like a good horror/suspense movie.
The first book, The Strain, sets up the situation. An airplane lands at JFK. All the lights are out and everyone is dead. Infectious disease is the first theory and CDC doctor Dr. Ephraim "Eph" Goodweather is assigned to the puzzling (and creepy) case. In other places in the city, the players are being prepared for what is to become, by the second book, a full blown epidemic.
By the second book, most of the characters have met and the origin of the vampires are slowly being revealed, mostly through the scholar Abraham Setrakian, who has tangled with the creatures before in his long life.
The third book is the endgame. What was a vampire novel has now turned post apocalyptic. Humans are farmed for blood and our heroes are fast running out of options to destroy the vampire menace.
As I said, the mythology is what I find most interesting about vampire literature. In this case, vampirism has a biological basis. It is parasitic in nature, and contained in capillary worms that can burrow into a human body. Once it is the bloodstream, it changes the host to make it more hospitable, shedding of necessary things such as hair and fingernails and growing a long stinger which is used as a weapon and as a way of extracting blood from the victim.
However, there is also a mystical side to the story wherein there are 7 ancients, the original vampires, whose blood worms seem to have become sentient and can transfer their consciousness to another body when one is destroyed. They can only be completely destroyed by nuking their birth places.
The series is action packed, exciting and a pretty interesting take on vampires.